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In eosinophilic bronchiectasis, a combined analysis of 2 trials found that patients with peripheral blood eosinophilia, but without asthma, allergic bronchopulmonary aspergillosis (ABPA), or COPD, experienced fewer exacerbations and hospitalizations after 6 months of ICS treatment.72 Another analysis showed mixed results, indicating that inhaled fluticasone, but not budesonide, significantly improved quality of life in these patients.73 Other treatments include monoclonal antibodies targeting elevated Th2 inflammation, such as anti-IL-5 or anti-IL-5 receptor monoclonal antibodies
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