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Like the wild-type MBP-PIF4 bHLH , the mB version, which alters only the basic motif, showed both dimers and high-molecular-weight multimers, whereas the multimer band was barely visible in the mBH version, which additionally targets the first helix (Fig
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Even when these reductions in bone mass are not evident, low dose glucocorticoid use is still associated with reduced bone strength (89)
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