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[DOI] [PubMed] [Google Scholar] 40.Aventaggiato M., Vernucci E., Barreca F., Russo M
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The brain is particularly vulnerable to oxidative injury due to its high metabolic activity, high content of redox-active transition metals that act as initiators of ROS generation via Fenton chemistry, high content of poly-unsaturated fatty acids (PUFAs) that are highly prone to lipid peroxidation, and limited mechanisms of antioxidative defense, among other reasons [76]
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